BEAMing and Droplet Digital PCR Analysis of Mutant IDH1 mRNA in Glioma Patient Serum and Cerebrospinal Fluid Extracellular Vesicles

BEAMing and Droplet Digital PCR Analysis of Mutant IDH1 mRNA in Glioma Patient Serum and Cerebrospinal Fluid Extracellular Vesicles

Development of biofluid-based molecular diagnostic tests for cancer is an important step towards tumor characterization and real-time monitoring in a minimally invasive fashion. Extracellular vesicles (EVs) are released from tumor cells into body fluids and can provide a powerful platform for tumor...

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Bibliographic Details
Main Authors: Walter W Chen, Leonora Balaj, Linda M Liau, Michael L Samuels, Steve K Kotsopoulos, Casey A Maguire, Lori LoGuidice, Horacio Soto, Matthew Garrett, Lin Dan Zhu, Sarada Sivaraman, Clark Chen, Eric T Wong, Bob S Carter, Fred H Hochberg, Xandra O Breakefield, Johan Skog
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
BEAMing PCR
biomarkers
cancer
extracellular vesicles
droplet digital PCR
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253116301615

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http://www.sciencedirect.com/science/article/pii/S2162253116301615

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