The Kidney Clock Contributes to Timekeeping by the Master Circadian Clock

The Kidney Clock Contributes to Timekeeping by the Master Circadian Clock

The kidney harbors one of the strongest circadian clocks in the body. Kidney failure has long been known to cause circadian sleep disturbances. Using an adenine-induced model of chronic kidney disease (CKD) in mice, we probe the possibility that such sleep disturbances originate from aberrant circad...

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Bibliographic Details
Main Authors: Jihwan Myung, Mei-Yi Wu, Chun-Ya Lee, Amalia Ridla Rahim, Vuong Hung Truong, Dean Wu, Hugh David Piggins, Mai-Szu Wu
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:International Journal of Molecular Sciences
Subjects:
circadian clocks
systemic clocks
CKD
kidney
SCN
hierarchical organization
Online Access:https://www.mdpi.com/1422-0067/20/11/2765

Internet

https://www.mdpi.com/1422-0067/20/11/2765

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