Biomarkers for Lysosomal Storage Disorders with an Emphasis on Mass Spectrometry

Lysosomal storage disorders (LSDs) are characterized by an accumulation of various substances, such as sphingolipids, mucopolysaccharides, and oligosaccharides. The LSD enzymes responsible for the catabolism are active at acidic pH in the lysosomal compartment. In addition to the classically establi...

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Bibliographic Details
Main Authors: Ryuichi Mashima, Torayuki Okuyama, Mari Ohira
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/8/2704