Association of <it>MTHFR </it>gene polymorphisms with breast cancer survival

<p>Abstract</p> <p>Background</p> <p>Two functional single nucleotide polymorphisms (SNPs) in the 5,10-methylenetetrahydrofolate reductase (<it>MTHFR</it>) gene, C677T and A1298C, lead to decreased enzyme activity and affect chemosensitivity of tumor cells....

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Bibliographic Details
Main Authors: Mechanic Leah E, Goodman Julie E, Howe Tiffany M, Boersma Brenda J, Martin Damali N, Chanock Stephen J, Ambs Stefan
Format: Article
Language:English
Published: BMC 2006-10-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/6/257