A Hepatocyte FOXN3-α Cell Glucagon Axis Regulates Fasting Glucose

A Hepatocyte FOXN3-α Cell Glucagon Axis Regulates Fasting Glucose

Summary: The common genetic variation at rs8004664 in the FOXN3 gene is independently and significantly associated with fasting blood glucose, but not insulin, in non-diabetic humans. Recently, we reported that primary hepatocytes from rs8004664 hyperglycemia risk allele carriers have increased FOXN...

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Bibliographic Details
Main Authors: Santhosh Karanth, J.D. Adams, Maria de los Angeles Serrano, Ezekiel B. Quittner-Strom, Judith Simcox, Claudio J. Villanueva, Lale Ozcan, William L. Holland, H. Joseph Yost, Adrian Vella, Amnon Schlegel
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718309495

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http://www.sciencedirect.com/science/article/pii/S2211124718309495

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