Serum PINP, PIIINP, galectin-3 and ST2 as Surrogates of Myocardial Fibrosis and Echocardiographic Left Venticular Diastolic Filling Properties

Objectives and Background. Serum biomarkers have been proposed to reflect fibrosis of several human tissues, but their specific role in the detection of myocardial fibrosis has not been well established. We studied the association between N-terminal propeptide of type I and III procollagen (PINP, PI...

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Main Authors: E Samuli Lepojärvi, Olli-Pekka ePiira, Eija ePääkkö, Eveliina eLammentausta, Juha eRisteli, Johanna A Miettinen, Juha S Perkiömäki, Heikki V Huikuri, M Juhani Junttila
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Physiology
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Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00200/full