MiR-30a-5p confers cisplatin resistance by regulating IGF1R expression in melanoma cells

MiR-30a-5p confers cisplatin resistance by regulating IGF1R expression in melanoma cells

Abstract Background Melanoma is notoriously resistant to all current modalities of cancer therapies including chemotherapy. In recent years, microRNAs (miRNAs) have emerged as molecular regulators in the development and progression of melanoma. However, the relationship between microRNA and chemo-re...

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Bibliographic Details
Main Authors: Yuxia Li, Jie Zhang, Yajing Liu, Bingyue Zhang, Fubo Zhong, Shubin Wang, Zhengyu Fang
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Cancer
Subjects:
Melanoma
Cisplatin
miR-30a-5p
IGF1R
Chemo-resistance
Online Access:http://link.springer.com/article/10.1186/s12885-018-4233-9

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http://link.springer.com/article/10.1186/s12885-018-4233-9

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