AEG-1 is involved in hypoxia-induced autophagy and decreases chemosensitivity in T-cell lymphoma

AEG-1 is involved in hypoxia-induced autophagy and decreases chemosensitivity in T-cell lymphoma

Abstract Background This study was to examine the link between astrocyte elevated gene-1 (AEG-1) and hypoxia induced-chemoresistance in T-cell non-Hodgkin’s lymphoma (T-NHL), as well as the underlying molecular mechanisms. Methods Expression of AEG-1, LC3-II, and Beclin-1 were initially examined in...

Full description

Bibliographic Details
Main Authors: Jiaqin Yan, Junhui Zhang, Xudong Zhang, Xin Li, Ling Li, Zhaoming Li, Renyin Chen, Lei Zhang, Jingjing Wu, Xinhua Wang, Zhenchang Sun, Xiaorui Fu, Yu Chang, Feifei Nan, Hui Yu, Xiaolong Wu, Xiaoyan Feng, Wencai Li, Mingzhi Zhang
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Molecular Medicine
Subjects:
Astrocyte elevated gene-1 (AEG-1)
T-cell non-Hodgkin’s lymphoma (T-NHL)
Hypoxia
Autophagy
Chemosensitivity
Online Access:http://link.springer.com/article/10.1186/s10020-018-0033-6

Internet

http://link.springer.com/article/10.1186/s10020-018-0033-6

Similar Items