A Validated Multiscale In-Silico Model for Mechano-sensitive Tumour Angiogenesis and Growth.

Vascularisation is a key feature of cancer growth, invasion and metastasis. To better understand the governing biophysical processes and their relative importance, it is instructive to develop physiologically representative mathematical models with which to compare to experimental data. Previous stu...

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Bibliographic Details
Main Authors: Vasileios Vavourakis, Peter A Wijeratne, Rebecca Shipley, Marilena Loizidou, Triantafyllos Stylianopoulos, David J Hawkes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1005259