Glycation of H1 Histone by 3-Deoxyglucosone: Effects on Protein Structure and Generation of Different Advanced Glycation End Products.

Advanced glycation end products (AGEs) culminate from the non-enzymatic reaction between a free carbonyl group of a reducing sugar and free amino group of proteins. 3-deoxyglucosone (3-DG) is one of the dicarbonyl species that rapidly forms several protein-AGE complexes that are believed to be invol...

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Bibliographic Details
Main Authors: Jalaluddin Mohammad Ashraf, Gulam Rabbani, Saheem Ahmad, Qambar Hasan, Rizwan Hasan Khan, Khursheed Alam, Inho Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4487796?pdf=render