Weighted likelihood inference of genomic autozygosity patterns in dense genotype data

Weighted likelihood inference of genomic autozygosity patterns in dense genotype data

Abstract Background Genomic regions of autozygosity (ROA) arise when an individual is homozygous for haplotypes inherited identical-by-descent from ancestors shared by both parents. Over the past decade, they have gained importance for understanding evolutionary history and the genetic basis of comp...

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Bibliographic Details
Main Authors: Alexandra Blant, Michelle Kwong, Zachary A. Szpiech, Trevor J. Pemberton
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Genomics
Subjects:
Autozygosity
Consanguinity
Homozygosity
Identity by descent
Inbreeding
Human populations
Online Access:http://link.springer.com/article/10.1186/s12864-017-4312-3

Internet

http://link.springer.com/article/10.1186/s12864-017-4312-3

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