Engineering an Antibody V Gene-Selective Vaccine

Engineering an Antibody V Gene-Selective Vaccine

The ligand-binding surface of the B cell receptor (BCR) is formed by encoded and non-encoded antigen complementarity determining regions (CDRs). Genetically reproducible or ‘public’ antibodies can arise when the encoded CDRs play deterministic roles in antigen recognition, notably within human broad...

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Bibliographic Details
Main Authors: Larance Ronsard, Ashraf S. Yousif, Julianne Peabody, Vintus Okonkwo, Pascal Devant, Alemu Tekewe Mogus, Ralston M. Barnes, Daniel Rohrer, Nils Lonberg, David Peabody, Bryce Chackerian, Daniel Lingwood
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
antibody
B cell receptor
lineage
VLP
prime
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.730471/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.730471/full

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