The Hypoactivity Associated with the Repeated Exposure to Atrazine Is Related to Decreases in the Specific Binding to D1-DA Receptors in the Striatum of Rats

The herbicide atrazine (ATR) has a potential toxic effect on the neuronal circuits of the brain, specifically on two major dopaminergic pathways: the nigrostriatal and mesolimbic circuits. In this work, we repeatedly exposed adult male Sprague-Dawley rats to 6 injections of 100 mg ATR/kg of body wei...

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Bibliographic Details
Main Authors: José Abraham Márquez-Ramos, Isela Hernández-Plata, Mauricio Díaz-Muñoz, Verónica M. Rodríguez
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2017/2169212