RhoA GTPase phosphorylated at tyrosine 42 by src kinase binds to β-catenin and contributes transcriptional regulation of vimentin upon Wnt3A

In the Wnt canonical pathway, Wnt3A has been known to stabilize β-catenin. In the non-canonical Wnt signaling pathway, Wnt is known to activate Rho GTPases. The correlation between canonical and non-canonical pathways by Wnt signaling, however, has not been well elucidated. Here, we identified that...

Full description

Bibliographic Details
Main Authors: Jae-Gyu Kim, Shohel Mahmud, Jung Ki Min, Yoon-Beom Lee, Hyunbin Kim, Dong-Chul Kang, Hwee-Seon Park, Jihye Seong, Jae-Bong Park
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Redox Biology
Subjects:
Src
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720310478