Guggulsterone targets smokeless tobacco induced PI3K/Akt pathway in head and neck cancer cells.

Guggulsterone targets smokeless tobacco induced PI3K/Akt pathway in head and neck cancer cells.

Epidemiological association of head and neck cancer with smokeless tobacco (ST) emphasizes the need to unravel the molecular mechanisms implicated in cancer development, and identify pharmacologically safe agents for early intervention and prevention of disease recurrence. Guggulsterone (GS), a bios...

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Bibliographic Details
Main Authors: Muzafar A Macha, Ajay Matta, Shyam Singh Chauhan, K W Michael Siu, Ranju Ralhan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3044714?pdf=render

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http://europepmc.org/articles/PMC3044714?pdf=render

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