Mechanisms of valproate-induced teratogenesis

Mechanisms of valproate-induced teratogenesis

The risks associated with in utero antiepileptic drug (AED) exposure are of great importance for both epileptic women and their offspring. This review considers the basic mechanisms of valproate-induced teratogenesis. It discusses the mechanisms of fetal valproic acid accumulation, oxidative stress,...

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Bibliographic Details
Main Authors: D. V. Dmitrenko, N. A. Shnaider, I. G. Strotskaya, A. S. Kichkaylo, S. N. Zobova
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2017-06-01
Series:Nevrologiâ, Nejropsihiatriâ, Psihosomatika
Subjects:
antiepileptic drugs
valproic acid
teratogenesis
epilepsy
congenital malformations
pregnancy
Online Access:https://nnp.ima-press.net/nnp/article/view/734

Internet

https://nnp.ima-press.net/nnp/article/view/734

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