Impact of withholding breastfeeding at the time of vaccination on the immunogenicity of oral rotavirus vaccine--a randomized trial.

Breast milk contains anti-rotavirus IgA antibodies and other innate immune factors that inhibit rotavirus replication in vitro. These factors could diminish the immunogenicity of oral rotavirus vaccines, particularly if breastfeeding occurs close to the time of vaccine administration.Between April 2...

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Bibliographic Details
Main Authors: Asad Ali, Abdul Momin Kazi, Margaret M Cortese, Jessica A Fleming, SungSil Moon, Umesh D Parashar, Baoming Jiang, Monica M McNeal, Duncan Steele, Zulfiqar Bhutta, Anita K M Zaidi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4452702?pdf=render