A hierarchical Bayesian model for understanding the spatiotemporal dynamics of the intestinal epithelium.

Our work addresses two key challenges, one biological and one methodological. First, we aim to understand how proliferation and cell migration rates in the intestinal epithelium are related under healthy, damaged (Ara-C treated) and recovering conditions, and how these relations can be used to ident...

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Bibliographic Details
Main Authors: Oliver J Maclaren, Aimée Parker, Carmen Pin, Simon R Carding, Alastair J M Watson, Alexander G Fletcher, Helen M Byrne, Philip K Maini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-07-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1005688