P4 Aldosterone-Induced Vascular Dysfunction by Decreasing Nuclear Factor Erythroid 2–Related Factor 2 Activity and Increasing Reactive Oxygen Species Generation

Introduction: Chronic increases in aldosterone (Aldo) levels (hyperaldosteronism) increases blood pressure and induces hypertension. In the cardiovascular system, Aldo stimulates reactive oxygen species (ROS) generation. ROS contribute to vascular dysfunction by increasing vascular smooth muscle con...

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Bibliographic Details
Main Authors: Daniel Rodrigues, Tiago Januário da Costa, Rafael Menezes da Costa, Rita de Cássia Aleixo Tostes Passaglia
Format: Article
Language:English
Published: Atlantis Press 2020-02-01
Series:Artery Research
Online Access:https://www.atlantis-press.com/article/125934413/view