Overexpression of an outer membrane protein associated with decreased susceptibility to carbapenems in Proteus mirabilis.

Proteus mirabilis isolates commonly have decreased susceptibility to imipenem. Previously, we found P. mirabilis hfq mutant was more resistant to imipenem and an outer membrane protein (OMP) could be involved. Therefore, we investigated the role of this OMP in carbapenem susceptibility. By SDS-PAGE...

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Bibliographic Details
Main Authors: Yi-Lin Tsai, Min-Cheng Wang, Po-Ren Hsueh, Ming-Che Liu, Rouh-Mei Hu, Yue-Jin Wu, Shwu-Jen Liaw
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4355480?pdf=render