The IL-33/ST2 axis affects tumor growth by regulating mitophagy in macrophages and reprogramming their polarization
Objective: Macrophages are a major component of the tumor microenvironment. M1 macrophages secrete pro-inflammatory factors that inhibit tumor growth and development, whereas tumor-associated macrophages (TAMs) mainly exhibit an M2 phenotype. Our previous studies have shown that the interleukin-33/S...
Main Authors: | Huadan Xu, Dong Li, Jiaoyan Ma, Yuanxin Zhao, Long Xu, Rui Tian, Yanan Liu, Liankun Sun, Jing Su |
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Format: | Article |
Language: | English |
Published: |
China Anti-Cancer Association
2021-02-01
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Series: | Cancer Biology & Medicine |
Subjects: | |
Online Access: | http://www.cancerbiomed.org/index.php/cocr/article/view/1778 |
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