A multiscale agent-based in silico model of liver fibrosis progression

A multiscale agent-based in silico model of liver fibrosis progression

Chronic hepatic inflammation involves a complex interplay of inflammatory and mechanical influences, ultimately manifesting in a characteristic histopathology of liver fibrosis. We created an agent-based model (ABM) of liver tissue in order to computationally examine the consequence of liver inflam...

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Bibliographic Details
Main Authors: Joyeeta eDutta-Moscato, Alexey eSolovyev, Qi eMi, Taichiro eNishikawa, Alejandro eSoto-Gutierrez, Ira J. Fox, Yoram eVodovotz
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Computer Simulation
Hepatocytes
Inflammation
cirrhosis
elastography
Online Access:http://journal.frontiersin.org/Journal/10.3389/fbioe.2014.00018/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fbioe.2014.00018/full

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