Data and theory point to mainly additive genetic variance for complex traits.

The relative proportion of additive and non-additive variation for complex traits is important in evolutionary biology, medicine, and agriculture. We address a long-standing controversy and paradox about the contribution of non-additive genetic variation, namely that knowledge about biological pathw...

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Bibliographic Details
Main Authors: William G Hill, Michael E Goddard, Peter M Visscher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2265475?pdf=render