Knock down of heat shock protein 27 (HspB1) induces degradation of several putative client proteins.

Knock down of heat shock protein 27 (HspB1) induces degradation of several putative client proteins.

Hsp27 belongs to the heat shock protein family and displays chaperone properties in stress conditions by holding unfolded polypeptides, hence avoiding their inclination to aggregate. Hsp27 is often referenced as an anti-cancer therapeutic target, but apart from its well-described ability to interfer...

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Bibliographic Details
Main Authors: Benjamin Gibert, Bénédicte Eckel, Lydie Fasquelle, Maryline Moulin, Frantz Bouhallier, Vincent Gonin, Gregory Mellier, Stéphanie Simon, Carole Kretz-Remy, André-Patrick Arrigo, Chantal Diaz-Latoud
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3251601?pdf=render

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http://europepmc.org/articles/PMC3251601?pdf=render

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