Berberine Protects Mice Against Dextran Sulfate Sodium-Induced Colitis by Activating mTORC1 Pathway

Berberine Protects Mice Against Dextran Sulfate Sodium-Induced Colitis by Activating mTORC1 Pathway

Berberine is a plant alkaloid that can be extracted from many Chinese herbs. It has been reported that berberine could protect mice from ulcerative colitis, but the mechanism remains unclear. The current study’s aim was to determine the potential mechanism by which berberine exhibits its anti-inflam...

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Bibliographic Details
Main Authors: Qingjun Li, Xinyan Qu, Xiaogang Pang, Yue Song, Liyuan Chen, Qiuyue Xiao, Linlin Sun, Xiaolong Wang, Huimin Zhang, Dongmei Qi, Zhenguo Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Pharmacology
Subjects:
berberine
ulcerative colitis
metabolism of amino acid
mTORC1
Treg cells
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00786/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00786/full

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