Bmp4 Promotes a Brown to White-like Adipocyte Shift

While Bmp4 has a well-established role in the commitment of mesenchymal stem cells into the adipogenic lineage, its role in brown adipocyte formation and activity is not well defined. Here, we show that Bmp4 has a dual function in adipogenesis by inducing adipocyte commitment while inhibiting the ac...

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Bibliographic Details
Main Authors: Salvatore Modica, Leon G. Straub, Miroslav Balaz, Wenfei Sun, Lukas Varga, Patrik Stefanicka, Milan Profant, Eric Simon, Heike Neubauer, Barbara Ukropcova, Jozef Ukropec, Christian Wolfrum
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716309792