Luteolin Prevents Cardiometabolic Alterations and Vascular Dysfunction in Mice With HFD-Induced Obesity

Luteolin Prevents Cardiometabolic Alterations and Vascular Dysfunction in Mice With HFD-Induced Obesity

Purpose: Luteolin exerts beneficial effects against obesity-associated comorbidities, although its influence on vascular dysfunction remains undetermined. We examined the effects of luteolin on endothelial dysfunction in a mouse model of diet-induced obesity.Methods: Standard diet (SD) or high-fat d...

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Bibliographic Details
Main Authors: Daniela Gentile, Matteo Fornai, Carolina Pellegrini, Rocchina Colucci, Laura Benvenuti, Emiliano Duranti, Stefano Masi, Sara Carpi, Paola Nieri, Anna Nericcio, Francesca Garelli, Agostino Virdis, Laura Pistelli, Corrado Blandizzi, Luca Antonioli
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Pharmacology
Subjects:
obesity
high-fat diet
mice
vascular dysfunction
oxidative stress
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01094/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01094/full

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