Identification, mapping and relative quantitation of SARS-CoV-2 Spike glycopeptides by Mass-Retention Time Fingerprinting

Identification, mapping and relative quantitation of SARS-CoV-2 Spike glycopeptides by Mass-Retention Time Fingerprinting

Mapping multiple glycan species to the same peptide and location from shared retention time of glycopeptides with MS and HPLC, Chalk, Greenland et al. construct a detailed mass-retention time database for Spike protein glycopeptides. This allows any mass LC-MS laboratory to reliably identify and qua...

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Bibliographic Details
Main Authors: Rod Chalk, William E. P. Greenland, Tiago Moreira, Jesse Coker, Shubhashish M. M. Mukhopadhyay, Eleanor Williams, Charlotte Manning, Tina Bohstedt, Rama McCrorie, Alejandra Fernandez-Cid, Nicola A. Burgess-Brown
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02455-w

Internet

https://doi.org/10.1038/s42003-021-02455-w

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