Graph embedding and unsupervised learning predict genomic sub-compartments from HiC chromatin interaction data

Accurate identification of sub-compartments from chromatin interaction data remains a challenge. Here, the authors introduce an algorithm combining graph embedding and unsupervised learning to predict sub-compartments using Hi-C data.

Bibliographic Details
Main Authors: Haitham Ashoor, Xiaowen Chen, Wojciech Rosikiewicz, Jiahui Wang, Albert Cheng, Ping Wang, Yijun Ruan, Sheng Li
Format: Article
Language:English
Published: Nature Publishing Group 2020-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14974-x