Sphingolipid Metabolism: New Insight into Ceramide-Induced Lipotoxicity in Muscle Cells

Sphingolipid Metabolism: New Insight into Ceramide-Induced Lipotoxicity in Muscle Cells

Insulin-resistance is a characteristic feature of type 2 diabetes (T2D) and plays a major role in the pathogenesis of this disease. Skeletal muscles are quantitatively the biggest glucose users in response to insulin and are considered as main targets in development of insulin-resistance. It is now...

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Bibliographic Details
Main Authors: Cécile L. Bandet, Sophie Tan-Chen, Olivier Bourron, Hervé Le Stunff, Eric Hajduch
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
sphingolipids
ceramide
insulin
diabetes
DAG
Online Access:https://www.mdpi.com/1422-0067/20/3/479

Internet

https://www.mdpi.com/1422-0067/20/3/479

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