Sphingolipid Metabolism: New Insight into Ceramide-Induced Lipotoxicity in Muscle Cells
Insulin-resistance is a characteristic feature of type 2 diabetes (T2D) and plays a major role in the pathogenesis of this disease. Skeletal muscles are quantitatively the biggest glucose users in response to insulin and are considered as main targets in development of insulin-resistance. It is now...
Main Authors: | Cécile L. Bandet, Sophie Tan-Chen, Olivier Bourron, Hervé Le Stunff, Eric Hajduch |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-01-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/20/3/479 |
Similar Items
-
Sphingolipid Metabolism and Signaling in Skeletal Muscle: From Physiology to Physiopathology
by: Sophie Tan-Chen, et al.
Published: (2020-08-01) -
Roles of Sphingolipid Metabolism in Pancreatic β Cell Dysfunction Induced by Lipotoxicity
by: Julien Véret, et al.
Published: (2014-06-01) -
Overview of concepts of the sphingolipid metabolism
by: Galyna Storozhenko, et al.
Published: (2021-06-01) -
Ceramide Synthases Are Attractive Drug Targets for Treating Metabolic Diseases
by: Suryaprakash Raichur
Published: (2020-07-01) -
Deciphering the Link Between Hyperhomocysteinemia and Ceramide Metabolism in Alzheimer-Type Neurodegeneration
by: Hervé Le Stunff, et al.
Published: (2019-07-01)