Dietary omega-3 fatty acids modulate the eicosanoid profile in man primarily via the CYP-epoxygenase pathway[S]

Dietary omega-3 fatty acids modulate the eicosanoid profile in man primarily via the CYP-epoxygenase pathway[S]

Cytochrome P450 (CYP)-dependent metabolites of arachidonic acid (AA) contribute to the regulation of cardiovascular function. CYP enzymes also accept EPA and DHA to yield more potent vasodilatory and potentially anti-arrhythmic metabolites, suggesting that the endogenous CYP-eicosanoid profile can b...

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Bibliographic Details
Main Authors: Robert Fischer, Anne Konkel, Heidrun Mehling, Katrin Blossey, Andrej Gapelyuk, Niels Wessel, Clemens von Schacky, Ralf Dechend, Dominik N. Muller, Michael Rothe, Friedrich C. Luft, Karsten Weylandt, Wolf-Hagen Schunck
Format: Article
Language:English
Published: Elsevier 2014-06-01
Series:Journal of Lipid Research
Subjects:
cytochrome P450
lipidomics
nutrition
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520352780

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http://www.sciencedirect.com/science/article/pii/S0022227520352780

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