Dietary omega-3 fatty acids modulate the eicosanoid profile in man primarily via the CYP-epoxygenase pathway[S]
Cytochrome P450 (CYP)-dependent metabolites of arachidonic acid (AA) contribute to the regulation of cardiovascular function. CYP enzymes also accept EPA and DHA to yield more potent vasodilatory and potentially anti-arrhythmic metabolites, suggesting that the endogenous CYP-eicosanoid profile can b...
Main Authors: | Robert Fischer, Anne Konkel, Heidrun Mehling, Katrin Blossey, Andrej Gapelyuk, Niels Wessel, Clemens von Schacky, Ralf Dechend, Dominik N. Muller, Michael Rothe, Friedrich C. Luft, Karsten Weylandt, Wolf-Hagen Schunck |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-06-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520352780 |
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