12/15-Lipoxygenase Regulates IL-33-Induced Eosinophilic Airway Inflammation in Mice

12/15-Lipoxygenase Regulates IL-33-Induced Eosinophilic Airway Inflammation in Mice

Dysregulated fatty acid metabolism is clinically associated with eosinophilic allergic diseases, including severe asthma and chronic rhinosinusitis. This study aimed to demonstrate the role of 12/15-lipoxygenase (12/15-LOX) in interleukin (IL)-33-induced eosinophilic airway inflammation; to this end...

Full description

Bibliographic Details
Main Authors: Jun Miyata, Yoshiyuki Yokokura, Kazuyo Moro, Hiroyuki Arai, Koichi Fukunaga, Makoto Arita
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
12/15-lipoxygenase
IL-33
docosahexaenoic acid
14(S)-HDoHE
group 2 innate lymphoid cell
lipidomics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.687192/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.687192/full

Similar Items