In vitro maturation of dopaminergic neurons derived from mouse embryonic stem cells: implications for transplantation.

The obvious motor symptoms of Parkinson's disease result from a loss of dopaminergic neurons from the substantia nigra. Embryonic stem cell-derived neural progenitor or precursor cells, adult neurons and fetal midbrain tissue have all been used to replace dying dopaminergic neurons. Transplante...

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Bibliographic Details
Main Authors: Bradley Watmuff, Colin W Pouton, John M Haynes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3285205?pdf=render