Dynamic conversion of cell sorting patterns in aggregates of embryonic stem cells with differential adhesive affinity

Abstract Background Mammalian early development comprises the proliferation, differentiation, and self-assembly of the embryonic cells. The classic experiment undertaken by Townes and Holtfreter demonstrated the ability of dissociated embryonic cells to sort and self-organize spontaneously into the...

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Bibliographic Details
Main Authors: Jeffrey D. Tse, Robert Moore, Yue Meng, Wensi Tao, Elizabeth R. Smith, Xiang-Xi Xu
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Developmental Biology
Subjects:
Online Access:https://doi.org/10.1186/s12861-020-00234-0