Dynamic conversion of cell sorting patterns in aggregates of embryonic stem cells with differential adhesive affinity

Dynamic conversion of cell sorting patterns in aggregates of embryonic stem cells with differential adhesive affinity

Abstract Background Mammalian early development comprises the proliferation, differentiation, and self-assembly of the embryonic cells. The classic experiment undertaken by Townes and Holtfreter demonstrated the ability of dissociated embryonic cells to sort and self-organize spontaneously into the...

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Bibliographic Details
Main Authors: Jeffrey D. Tse, Robert Moore, Yue Meng, Wensi Tao, Elizabeth R. Smith, Xiang-Xi Xu
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Developmental Biology
Subjects:
Embryoid body
Embryonic stem (ES) cells
Cell sorting
Morphogenesis
Cell spontaneous assembly
Embryonic development
Online Access:https://doi.org/10.1186/s12861-020-00234-0

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