An adequately robust early TNF-alpha response is a hallmark of survival following trauma/hemorrhage.

An adequately robust early TNF-alpha response is a hallmark of survival following trauma/hemorrhage.

BACKGROUND:Trauma/hemorrhagic shock (T/HS) results in cytokine-mediated acute inflammation that is generally considered detrimental. METHODOLOGY/PRINCIPAL FINDINGS:Paradoxically, plasma levels of the early inflammatory cytokine TNF-alpha (but not IL-6, IL-10, or NO(2) (-)/NO(3) (-)) were significant...

Full description

Bibliographic Details
Main Authors: Rajaie Namas, Ali Ghuma, Andres Torres, Patricio Polanco, Hernando Gomez, Derek Barclay, Lisa Gordon, Sven Zenker, Hyung Kook Kim, Linda Hermus, Ruben Zamora, Matthew R Rosengart, Gilles Clermont, Andrew Peitzman, Timothy R Billiar, Juan Ochoa, Michael R Pinsky, Juan Carlos Puyana, Yoram Vodovotz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2794373?pdf=render

Internet

http://europepmc.org/articles/PMC2794373?pdf=render

Similar Items