HE4 (WFDC2) Promotes Tumor Growth in Endometrial Cancer Cell Lines

HE4 (WFDC2) Promotes Tumor Growth in Endometrial Cancer Cell Lines

HE4, also known as WFDC2, is a useful biomarker for ovarian cancer when either used alone or in combination with CA125. HE4 is also overexpressed in endometrial cancer (EC), but its function in cancer cells is not clear. In this study, we investigate the role of HE4 in EC progression. An HE4-overexp...

Full description

Bibliographic Details
Main Authors: Sean Dowdy, Shi-Wen Jiang, Ronny Drapkin, Russell Broaddus, Karl Podratz, Edward Klatt, Dong Chen, Andrea Mariani, Haibin Chen, Jinping Li
Format: Article
Language:English
Published: MDPI AG 2013-03-01
Series:International Journal of Molecular Sciences
Subjects:
endometrial cancer
human epididymis protein 4 (HE4)
HE4 variant
proliferation
invasion
colony formation
tumorigenesis
Online Access:http://www.mdpi.com/1422-0067/14/3/6026

Internet

http://www.mdpi.com/1422-0067/14/3/6026

Similar Items