The presence of alpha-catenin in the VE-cadherin complex is required for efficient transendothelial migration of leukocytes

<p>The majority of the leukocytes cross the endothelial lining of the vessels through cell-cell junctions. The junctional protein Vascular Endothelial (VE)-cadherin is transiently re-distributed from sites of cell-cell contacts during passage of leukocytes. VE-cadherin is part of a protein com...

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Bibliographic Details
Main Author: Jaap D. van Buul, Floris P. van Alphen, Peter L. Hordijk
Format: Article
Language:English
Published: Ivyspring International Publisher 2009-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v05p0695.htm