Palmitate Induces TRB3 Expression and Promotes Apoptosis in Human Liver Cells

Palmitate Induces TRB3 Expression and Promotes Apoptosis in Human Liver Cells

Background/Aims: Parenteral nutrition-associated liver disease (PNALD) is a major complication for patients who require long-term parenteral nutrition. Treatment options for PNALD are limited and its pathogenesis is poorly understood. Tribbles homolog 3 (TRB3) is a pseudokinase that modulates many s...

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Bibliographic Details
Main Authors: Weihui Yan, Ying Wang, Yongtao Xiao, Jie Wen, Jiang Wu, Lei Du, Wei Cai
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
Tribbles homolog 3
Palmitate
Endoplasmic reticulum stress
Cell viability
Akt phosphorylation
Online Access:http://www.karger.com/Article/FullText/358655

Internet

http://www.karger.com/Article/FullText/358655

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