Voluntary running exercise protects against sepsis-induced early inflammatory and pro-coagulant responses in aged mice

Abstract Background Despite many animal studies and clinical trials, mortality in sepsis remains high. This may be due to the fact that most experimental studies of sepsis employ young animals, whereas the majority of septic patients are elderly (60 − 70 years). The objective of the present study wa...

Full description

Bibliographic Details
Main Authors: Karel Tyml, Scott Swarbreck, Cynthia Pape, Dan Secor, James Koropatnick, Qingping Feng, Ruud A. W. Veldhuizen, Sean E. Gill
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Critical Care
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13054-017-1783-1