Methylation of Estrogen Receptor 1 Gene in the Paraspinal Muscles of Girls with Idiopathic Scoliosis and Its Association with Disease Severity

Methylation of Estrogen Receptor 1 Gene in the Paraspinal Muscles of Girls with Idiopathic Scoliosis and Its Association with Disease Severity

Idiopathic scoliosis (IS) is a multifactorial disease with epigenetic modifications. Tissue dependent and differentially methylated regions (T-DMRs) may regulate tissue-specific expression of the estrogen receptor 1 gene (<i>ESR1</i>). This study aimed to analyze methylation levels withi...

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Bibliographic Details
Main Authors: Piotr Janusz, Małgorzata Chmielewska, Mirosław Andrusiewicz, Małgorzata Kotwicka, Tomasz Kotwicki
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Genes
Subjects:
spinal curvatures
scoliosis
idiopathic
DNA methylation
pyrosequencing
estrogen receptor 1
Online Access:https://www.mdpi.com/2073-4425/12/6/790

Internet

https://www.mdpi.com/2073-4425/12/6/790

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