Brain Atrophy Mediates the Relationship between Misfolded Proteins Deposition and Cognitive Impairment in Parkinson’s Disease

Brain Atrophy Mediates the Relationship between Misfolded Proteins Deposition and Cognitive Impairment in Parkinson’s Disease

Parkinson’s disease is associated with cognitive decline, misfolded protein deposition and brain atrophy. We herein hypothesized that structural abnormalities may be mediators between plasma misfolded proteins and cognitive functions. Neuropsychological assessments including five domains (attention,...

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Bibliographic Details
Main Authors: Chiun-Chieh Yu, Chia-Yin Lu, Meng-Hsiang Chen, Yueh-Sheng Chen, Cheng-Hsien Lu, Yi-Yun Lin, Kun-Hsien Chou, Wei-Che Lin
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Journal of Personalized Medicine
Subjects:
cognition
dementia
gray matter atrophy
misfolding protein
Parkinson’s disease
Online Access:https://www.mdpi.com/2075-4426/11/8/702

Internet

https://www.mdpi.com/2075-4426/11/8/702

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