Synapse maintenance is impacted by ATAT-2 tubulin acetyltransferase activity and the RPM-1 signaling hub

Synapse maintenance is impacted by ATAT-2 tubulin acetyltransferase activity and the RPM-1 signaling hub

Synapse formation is comprised of target cell recognition, synapse assembly, and synapse maintenance. Maintaining established synaptic connections is essential for generating functional circuitry and synapse instability is a hallmark of neurodegenerative disease. While many molecules impact synapse...

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Bibliographic Details
Main Authors: Melissa A Borgen, Andrew C Giles, Dandan Wang, Brock Grill
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-01-01
Series:eLife
Subjects:
synapse maintenance
synapse stability
C. elegans
tubulin acetyltransferase
ATAT-2
RPM-1
Online Access:https://elifesciences.org/articles/44040

Internet

https://elifesciences.org/articles/44040

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