Analysis of Microbiome Data in the Presence of Excess Zeros

Motivation: An important feature of microbiome count data is the presence of a large number of zeros. A common strategy to handle these excess zeros is to add a small number called pseudo-count (e.g., 1). Other strategies include using various probability models to model the excess zero counts. Alth...

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Bibliographic Details
Main Authors: Abhishek Kaul, Siddhartha Mandal, Ori Davidov, Shyamal D. Peddada
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02114/full