Regional Cerebral Perfusion and Cerebrovascular Reactivity in Elderly Controls With Subtle Cognitive Deficits

Background: Recent studies suggested that arterial spin labeling (ASL)-based measures of cerebral blood flow (CBF) as well as cerebral vasoreactivity to CO2 (CVR CO2) show significant alterations mainly in posterior neocortical areas both in mild cognitive impairment (MCI) and Alzheimer disease. It...

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Bibliographic Details
Main Authors: Merel van der Thiel, Cristelle Rodriguez, Dimitri Van De Ville, Panteleimon Giannakopoulos, Sven Haller
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
CO2
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00019/full