An improved Ras sensor for highly sensitive and quantitative FRET-FLIM imaging.

Ras is a signaling protein involved in a variety of cellular processes. Hence, studying Ras signaling with high spatiotemporal resolution is crucial to understanding the roles of Ras in many important cellular functions. Previously, fluorescence lifetime imaging (FLIM) of fluorescent resonance energ...

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Bibliographic Details
Main Authors: Ana F Oliveira, Ryohei Yasuda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3544822?pdf=render