Mycophenolate mofetil – 20 years of experience in treatment of rheumatic diseases

Mycophenolate mofetil (MMF) has been used in rheumatology for over 20 years. When transformed to the active metabolite of mycophenolic acid, it is a potent, selective, reversible inhibitor of inosine monophosphate dehydrogenase, a key enzyme of de novo purine synthesis, exerting a cytostatic effect...

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Bibliographic Details
Main Authors: Katarzyna Walkiewicz-Pielaszek, Monika Swacha, Barbara Bułło-Piontecka, Bolesław Rutkowski, Marzena Olesińska
Format: Article
Language:English
Published: Index Copernicus International S.A. 2015-02-01
Series:Postępy Higieny i Medycyny Doświadczalnej
Subjects:
Online Access:http://phmd.pl/gicid/01.3001.0010.4053