Inhibition of Autophagy Contributes to Melatonin-Mediated Neuroprotection Against Transient Focal Cerebral Ischemia in Rats

Melatonin, a natural product of the pineal gland, has been shown to protect against ischemic stroke, but the molecular mechanisms underlying its protective function are not fully understood. In the present study, we tested whether melatonin could protect against ischemia– reperfusion (I/R) injury to...

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Bibliographic Details
Main Authors: Yongqiu Zheng, Jincai Hou, Jianxun Liu, Mingjiang Yao, Lei Li, Bo Zhang, Hua Zhu, Zhong Wang
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319301860